ptenes

Nora Manoukian Forones

Currículo Lattes

E-mail: nmforones@unifesp.br


Selecione a Área ou Linha de Pesquisa para descrição.

Área: IDENTIFICAÇÃO E MONITORIZAÇÃO DE PROCESSOS PATOLÓGICOS

O aprofundamento do conhecimento etiopatogênico das doenças foi marcadamente influenciado pelo desenvolvimento de novos métodos de identificação e seguimento dos processos patológicos. Neste contexto, ferramentas laboratoriais e funcionais mais precisas e específicas acompanham as novas descobertas e a quebra de paradigmas do conhecimento vigente. O comportamento sistêmico das patologias no seu aspecto vascular, metabólico e inflamatório, na dependência do perfil genético do hospedeiro, responde de formas diferentes às intervenções com fármacos, agentes físicos e químicos. Logo, a medicina translacional, integrando os aspectos moleculares e celulares básicos às questões clínicas prementes ao diagnóstico das enfermidades, tem papel crucial em redefinir o papel dos procedimentos tradicionais em Medicina Interna.

Esta área de concentração reúne um grupo altamente sinérgico de linhas de pesquisa que investiga novos rumos para a interação entre biomarcadores moleculares e humorais com os determinantes genéticos de resistência e susceptibilidade a doenças de grande impacto epidemiológico no nosso meio, como as hepatites virais, o diabetes melitus, a cardiopatia chagásica e as neoplasias gastrointestinais. O mesmo enfoque é aplicado à terapias substitutivas de grande importância social, os transplantes renal e cardíaco, na qual a Instituição ocupa posição de vanguarda no cenário científico internacional. Adicionalmente, a pesquisa aplicada em métodos diagnósticos de avaliação funcional cardiovascular e gastrointestinal, visa o aperfeiçoamento e avanço metodológico com claras perspectivas de integração com os determinantes micro-estruturais das doenças sob investigação. Como corolário, espera-se desta Área de Concentração o desenvolvimento de produtos finais e procedimentos inovadores em Saúde, com clara relevância para o atendimento da demanda social brasileira. 

Linha de Pesquisa: NEOPLASIAS DO APARELHO DIGESTIVO

Estudar marcadores tumorais séricos ou teciduais que possam auxiliar na prevenção, no diagnóstico precoce, no prognóstico ou no tratamento dos doentes com cãncer; principalmente colorretal ou gástrico. Busca de biomarcadores no cancer utilizando a técnica da proteômica.

Linha de Pesquisa: BIOMARCADORES GENÉTICOS, IMUNOLÓGICOS E BIOQUÍMICOS PARA DIAGNÓSTICO PRECOCE E MONITORIZAÇÃO FUNCIONAL EM DOENÇAS PREVALENTES

Investigação de novos biomarcadores genéticos, imunológicos, bioquímicos e alterações tissulares microestruturais, utilizados no diagnóstico precoce, análise de progressão de processos patológicos e alterações funcionais em diferentes doenças prevalentes.



Orientações em Andamento:

Data de Matrícula Aluno Programa de Pós-Graduação Nível
01/05/2022 TASSIANE DE PAULA SUDBRACK Gastroenterologia (33009015012P2) MESTRADO
01/02/2022 GABRIEL CAIO DE SOUZA Medicina Translacional (33009015069P4) MESTRADO
01/12/2021 PAMELA SIMÕES DE ALMEIDA Gastroenterologia (33009015012P2) MESTRADO
01/10/2020 CECÍLIA ARAÚJO CARNEIRO LIMA Medicina Translacional (33009015069P4) DOUTORADO
01/10/2020 JERÔNIMO PAULO ASSIS DA SILVA Medicina Translacional (33009015069P4) DOUTORADO
01/10/2020 LUCIANA MATA DA SILVA Medicina Translacional (33009015069P4) DOUTORADO
01/09/2020 BRUNA BIGHETTI Gastroenterologia (33009015012P2) MESTRADO
01/08/2020 MARCOS DUMONT BONFIM SANTOS Gastroenterologia (33009015012P2) MESTRADO
01/08/2020 ROSEMEIRE LIMA LESSI Gastroenterologia (33009015012P2) MESTRADO

Orientações Concluídas:

Data de Titulação Aluno Programa de Pós-Graduação Nível
28/10/2021 MARILIA PEREIRA DA SILVA Medicina Translacional (33009015069P4) MESTRADO
30/09/2021 REBECA DE BARROS TADOKORO Medicina Translacional (33009015069P4) MESTRADO
18/12/2020 LILIAN NASCIMENTO ROSA Gastroenterologia (33009015012P2) MESTRADO
13/10/2020 NATHALIA VIANA E SILVA Tecnologias e Atenção à Saúde (33009015074P8) MESTRADO PROFISSIONAL
30/04/2020 ALINE RUFINO GONÇALVES Medicina Translacional (33009015069P4) MESTRADO
28/11/2019 TALITA MENDES DE OLIVEIRA Medicina Translacional (33009015069P4) DOUTORADO
31/10/2019 RAFAELA TONIN DESTRI Medicina Translacional (33009015069P4) MESTRADO
25/07/2019 GISLAINE FERNANDES SILVA Tecnologias e Atenção à Saúde (33009015074P8) MESTRADO PROFISSIONAL
30/05/2019 JEFFERSON SILVA MARTINS Medicina Translacional (33009015069P4) MESTRADO
25/10/2018 RONALDO ELIEZER MAMELLI Medicina Translacional (33009015069P4) MESTRADO
30/08/2018 PAMELA CARVALHO MUNIZ Tecnologias e Atenção à Saúde (33009015074P8) MESTRADO PROFISSIONAL
29/03/2018 TAÍS FERNANDA SANTOS MARCULINO Medicina Translacional (33009015069P4) MESTRADO
22/02/2018 CELIA APARECIDA MARQUES PIMENTA Gastroenterologia (33009015012P2) DOUTORADO
20/12/2017 PETRUS MOURA DE ANDRADE LIMA Medicina Translacional (33009015069P4) DOUTORADO
26/10/2017 MARIANA ABE VICENTE CAVAGNARI Gastroenterologia (33009015012P2) DOUTORADO
31/07/2017 ADIEL GOES DE FIGUEIREDO JUNIOR Gastroenterologia (33009015012P2) DOUTORADO
30/05/2017 RAELSON RODRIGUES MIRANDA Medicina Translacional (33009015069P4) MESTRADO
28/04/2017 CARLA CAROLINE DIAS RIBEIRO Gastroenterologia (33009015012P2) MESTRADO
25/10/2016 KATIA REGINA GUARDIA BARÃO Gastroenterologia (33009015012P2) DOUTORADO
26/07/2016 PATRICIA VALERIA PEREIRA SERAFIM Gastroenterologia (33009015012P2) DOUTORADO
23/12/2015 PEDRO NAZARETH AGUIAR JUNIOR Tecnologias e Atenção à Saúde (33009015074P8) MESTRADO PROFISSIONAL
31/03/2015 VERÔNICA MARQUES VIDIGAL Medicina Translacional (33009015069P4) DOUTORADO
30/11/2014 GISLAINE APARECIDA OZORIO Gastroenterologia (33009015012P2) MESTRADO
30/11/2014 ALEDSON VITOR FELIPE Gastroenterologia (33009015012P2) DOUTORADO
30/09/2014 TIAGO DONIZETTI DA SILVA Medicina Translacional (33009015069P4) DOUTORADO
20/12/2013 JACQUELINE MIRANDA DE LIMA Gastroenterologia (33009015012P2) DOUTORADO
31/07/2013 VANESSA MARIA DE LIMA PAZINE Medicina Translacional (33009015069P4) MESTRADO
29/05/2013 JULIANA DE OLIVEIRA Gastroenterologia (33009015012P2) MESTRADO
27/03/2013 ROSEANE MENDES SILVA Medicina Translacional (33009015069P4) MESTRADO
25/07/2012 MARIANA ABE VICENTE CAVAGNARI Medicina Translacional (33009015069P4) MESTRADO
29/02/2012 ADIEL GOES DE FIGUEIREDO JUNIOR Gastroenterologia (33009015012P2) MESTRADO
30/11/2011 CELIA APARECIDA MARQUES PIMENTA Gastroenterologia (33009015012P2) MESTRADO
31/08/2011 KATIA REGINA GUARDIA BARÃO Gastroenterologia (33009015012P2) MESTRADO
31/08/2011 GISELE PAULA VIEIRA Gastroenterologia (33009015012P2) MESTRADO
22/02/2011 LESSILEIA GOMES DE SOUZA Gastroenterologia (33009015012P2) MESTRADO
26/05/2010 ALEDSON VITOR FELIPE Gastroenterologia (33009015012P2) MESTRADO
26/05/2010 TIAGO DONIZETTI DA SILVA Gastroenterologia (33009015012P2) MESTRADO
26/11/2008 JACQUELINE MIRANDA DE LIMA Gastroenterologia (33009015012P2) MESTRADO
28/05/2008 LUCIANA ZAIA DELLA NEGRA POVEGLIANO Gastroenterologia (33009015012P2) DOUTORADO
31/10/2007 NARA ROSANA ANDRADE SANTOS Gastroenterologia (33009015012P2) MESTRADO
26/09/2007 MARTA MEDEIROS Gastroenterologia (33009015012P2) DOUTORADO
29/11/2006 VANIA MARIA BELETATE BAUERMEÍSTER Saúde Baseada em Evidências (33009015045P8) MESTRADO
25/10/2006 LIDIANE PEREIRA MAGALHÃES Gastroenterologia (33009015012P2) MESTRADO
30/11/2005 PATRICIA VALERIA PEREIRA SERAFIM Gastroenterologia (33009015012P2) MESTRADO
20/12/2004 VANESSA MARIA NUNES ROQUE Gastroenterologia (33009015012P2) MESTRADO
27/03/2002 SEVERINO MARCOS BORBA DE ARRUDA Gastroenterologia (33009015012P2) DOUTORADO
25/07/2001 MARTA MEDEIROS Gastroenterologia (33009015012P2) MESTRADO
27/06/2001 ESTHER ABRAMO GONÇALVES EIDELCHTEIN Gastroenterologia (33009015012P2) MESTRADO
20/12/2000 SANDRA VAISWAN MANDOWSKY Gastroenterologia (33009015012P2) MESTRADO
25/08/1999 CELINA TIZUKO FUJIYAMA OSHIMA Gastroenterologia (33009015012P2) DOUTORADO
01/02/1995 LUIZ ALBERTO CRAVO PINTO DE QUEIROZ Gastroenterologia (33009015012P2) MESTRADO
24/11/1993 VINICIUS FONTANESI BLUM Gastroenterologia (33009015012P2) MESTRADO

Artigos Completos Publicados em Periódicos Científicos:

  1. DE CASTRO JUNIOR, GILBERTO ; SEGALLA, JOSÉ GETÚLIO ; DE AZEVEDO, SÉRGIO JOBIM ; ANDRADE, CARLOS JOSÉ ; GRABARZ, DANIEL ; DE ARAÚJO LIMA FRANÇA, BRUNO ; DEL GIGLIO, AURO ; LAZARETTI, NICOLAS SILVA ; ÁLVARES, MARIA NUNES ; PEDRINI, JOSÉ LUIZ ; KUSSUMOTO, CELIO ; DE MATOS NETO, JOÃO NUNES ; FORONES, NORA MANOUKIAN ; FERNANDES JÚNIOR, HEZIO JADIR ; BORGES, GIULIANO ; GIROTTO, GUSTAVO ; DA SILVA, ISMAEL DALE COTRIM GUERREIRO ; MALUF-FILHO, FAUZE ; SKARE, NILS GUNNAR. A randomised phase II study of chemoradiotherapy with or without nimotuzumab in locally advanced oesophageal cancer: NICE trial. EUROPEAN JOURNAL OF CANCER. v. EUROPEAN JOURNAL OF CANCER, p. 21-30, 2018. http://dx.doi.org/10.1016/j.ejca.2017.10.005
  2. FIGUEIREDO JR, A. ; SERAFIM, P. V. P. ; AZZOLINI, A. ; Felipe AV ; Lo Turco E ; SILVA, I. D. C. G. ; Forones NM. Analysis of the Lipid Profile in Patients with Colorectal Cancer in Advanced Stages. Asian Pacific Journal of Cancer Prevention. v. Asian Pacific Journal of Cancer Prevention, p. 1287-1293, 2018. http://dx.doi.org/10.22034/APJCP.2018.19.5.1287
  3. Felipe AV ; Oliveira J ; Moraes AA ; Silva TD ; Forones NM. Reversal of Multidrug Resistance in an Epirubicin-Resistant Gastric Cancer Cell Subline. Asian Pacific Journal of Cancer Prevention. v. Asian Pacific Journal of Cancer Prevention, p. 1237-42, 2018. http://dx.doi.org/10.22034/APJCP.2018.19.5.1237
  4. VICENTE, CAROLINA MELONI ; DA SILVA, DAIANA APARECIDA ; SARTORIO, PRISCILA VERONICA ; SILVA, TIAGO DONIZETTI ; SAAD, SARHAN SYDNEY ; NADER, HELENA BONCIANI ; FORONES, NORA MANOUKIAN ; TOMA, LENY. Heparan Sulfate Proteoglycans in Human Colorectal Cancer. Analytical Cellular Pathology. v. Analytical Cellular Pathology, p. 1-10, 2018. http://dx.doi.org/10.1155/2018/8389595
  5. V, BUENO ; AL, MANDALITI ; NM, FORONES. Colorectal cancer: Ageing, myeloid-derived suppressor cells, and treatment: Report of two cases. Journal of Cancer Research e Therapy. v. Journal of Cancer Research e Therapy, p. 25-31, 2018. http://dx.doi.org/10.14312/2052-4994.2018-4
  6. VACCARO, CARLOS ALBERTO LÓPEZ-KOSTNER, FRANCISCO VALLE, ADRIANA DELLA PALMERO, EDENIR INEZ ROSSI, BENEDITO MAURO ANTELO, MARINA SOLANO, ANGELA CARRARO, DIRCE MARIA FORONES, NORA MANOUKIAN BOHORQUEZ, MABEL LINO-SILVA, LEONARDO S BULEJE, JOSE SPIRANDELLI, FLORENCIA ABE-SANDES, KIYOKO NASCIMENTO, IVANA SULLCAHUAMAN, YASSER SARROCA, CARLOS GONZALEZ, MARIA LAURA HERRANDO, ALBERTO IGNACIO ALVAREZ, KARIN NEFFA, FLORENCIA CAMPOS REIS GALVÃO, HENRIQUE ESPERON, PATRICIA GOLUBICKI, MARIANO CISTERNA, DANIEL , et al.CARDOSO, FLORENCIA C. From colorectal cancer pattern to the characterization of individuals at risk: picture for genetic research in Latin America. INTERNATIONAL JOURNAL OF CANCER. v. INTERNATIONAL JOURNAL OF CANCER, p. Oct 10. doi: 10, 2018. http://dx.doi.org/10.1002/ijc.31920
  7. RIECHELMANN, RACHEL P WESCHENFELDER, RUI F COSTA, FREDERICO P CHAVES ANDRADE, ALINE BERSCH OSVALD, ALESSANDRO QUIDUTE, ANA ROSA P DOS SANTOS, ALLAN HOFF, ANA AMÉLIA O GUMZ, BRENDA BUCHPIGUEL, CARLOS VILHEINA PEREIRA, BRUNO S MUNIZ LOURENÇO JUNIOR, DELMAR REIS DA ROCHA FILHO, DUILIO ANTUNES FONSECA, EDUARDO LINHARES RIELLO MELLO, EDUARDO FERRARI MAKDISSI, FABIO LUIZ WAECHTER, FABIO CARNEVALE, FRANCISCO CESAR COURA-FILHO, GEORGE B ANDRADE DE PAULO, GUSTAVO COLAGIOVANNI GIROTTO, GUSTAVO EVANGELISTA BEZERRA NETO, JOÃO GLASBERG, JOÃO CASALI-DA-ROCHA, JOSE CLAUDIO FLORINDA M REGO, JULIANA , et al.RODRIGUES DE MEIRELLES, LUCIANA HAJJAR, LUDHMILA MENEZES, MARCO BRONSTEIN, MARCELLO D TATIT SAPIENZA, MARCELO BARISSON VILLARES FRAGOSO, MARIA CANDIDA ALBERGARIA PEREIRA, MARIA ADELAIDE BARRAS, MILTON MANOUKIAN FORONES, NORA GALVÃO DO AMARAL, PAULO CEZAR SALLES SCORTEGAGNA DE MEDEIROS, RAPHAEL ARAUJO, RAPHAEL L C FRANÇA BEZERRA, REGIS OTAVIANO D?ALPINO PEIXOTO, RENATA AGUIAR JR, SAMUEL RIBEIRO JR, ULYSSES PFIFFER, TULIO HOFF, PAULO M COUTINHO, ANELISA K ; Guidelines for the management of neuroendocrine tumours by the Brazilian gastrointestinal tumour group. Guidelines for the management of neuroendocrine tumours by the Brazilian gastrointestinal tumour group. ECANCERMEDICALSCIENCE. v. ECANCERMEDICALSCIENCE, p. 716, 2017. http://dx.doi.org/10.3332/ecancer.2017.716
  8. OZORIO, GISLAINE APARECIDA ; BARÃO, KATIA ; FORONES, NORA MANOUKIAN. Cachexia Stage, Patient-Generated Subjective Global Assessment, Phase Angle, and Handgrip Strength in Patients with Gastrointestinal Cancer. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL. v. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, p. 1-8, 2017. http://dx.doi.org/10.1080/01635581.2017.1321130
  9. BARAO, KATIA ; ABE VICENTE CAVAGNARI, MARIANA ; SILVA FUCUTA, PATRICIA ; MANOUKIAN FORONES, NORA. Association Between Nutrition Status and Survival in Elderly Patients With Colorectal Cancer. NUTRITION IN CLINICAL PRACTICE. v. NUTRITION IN CLINICAL PRACTICE, p. 088453361770689, 2017. http://dx.doi.org/10.1177/0884533617706894
  10. MARQUES VIDIGAL, VERÔNICA ; AGUIAR JUNIOR, PEDRO NAZARETH ; DONIZETTI SILVA, TIAGO ; DE OLIVEIRA, JULIANA ; MARQUES PIMENTA, CÉLIA APARECIDA ; VITOR FELIPE, ALEDSON ; MANOUKIAN FORONES, NORA. Genetic polymorphisms of vitamin D metabolism genes and serum level of vitamin D in colorectal cancer. INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS. v. INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, p. 19.0, 2017. http://dx.doi.org/10.5301/ijbm.5000282
  11. SILVA, TIAGO D ; FELIPE, ALEDSON V ; Vidigal VM ; SAAD, S. S. ; Forones NM. DNA methylation profile of the DKK2 gene as a biomarker in patients with colorectal cancer. GENETICS AND MOLECULAR RESEARCH. v. GENETICS AND MOLECULAR RESEARCH, p. gmr16039816, 2017. http://dx.doi.org/10.4238/gmr16039816
  12. AGUIAR, PEDRO NAZARETH ; MUNIZ, THIAGO PIMENTEL ; MIRANDA, RAELSON RODRIGUES ; TADOKORO, HAKARU ; FORONES, NORA MANOUKIAN ; MONTEIRO, INES-DE-PAULA ; CASTELO-BRANCO, PEDRO ; JANJIGIAN, YELENA Y ; DE MELLO, RAMON ANDRADE. Current advances in targeted therapies for metastatic gastric cancer: improving patient care. Future Oncology. v. Future Oncology, p. 839-54, 2016. http://dx.doi.org/10.2217/fon.15.348
  13. Aguiar Jr P ; ARTIGGIANI NETO, R. ; FORONES NM. HER2 EXPRESSION AS A PROGNOSTIC FACTOR IN METASTATIC GASTRIC CANCER. Arquivos de Gastroenterologia (Online). v. Arquivos de Gastroenterologia (Online), p. 62-67, 2016. http://dx.doi.org/10.1590/s0004-28032016000200003
  14. Aguiar Jr P ; Stock G ; Barao K ; Forones NM. Chemotherapy for elderly patients with gastric cancer: experience of a brazilian center. GERIATRICS, GERONTOLOGY AND AGING. v. GERIATRICS, GERONTOLOGY AND AGING, p. 71-79, 2016. http://dx.doi.org/10.5327/z2447-211520161600004
  15. BERGEROT, C. D. ; PHILIP, E. J. ; BERGEROT, P. G. ; ELIAS, S. ; GUIMARAES, D. P. ; FORONES, N. M. ; BAIOCCHI, O. C. C. G. ; BATISTA, N. A. ; DE DOMENICO, E. B. L.. Quality Oncology Practice Initiative Can Guide and Improve Oncology Providers Training in Brazil. Journal of Global Oncology. v. Journal of Global Oncology, p. jgo. 2016.00614, 2016. http://dx.doi.org/10.1200/JGO.2016.006148
  16. VIDIGAL, VERÔNICA MARQUES ; SILVA, TIAGO DONIZETTI ; DE OLIVEIRA, JULIANA ; PIMENTA, CÉLIA APARECIDA MARQUES ; FELIPE, ALEDSON VITOR ; FORONES, NORA MANOUKIAN. Genetic polymorphisms of vitamin D receptor (VDR), CYP27B1 and CYP24A1 genes and the risk of colorectal cancer. The International Journal of Biological Markers (Testo stampato). v. The International Journal of Biological Markers (Testo stampato), p. 231-5, 2016. http://dx.doi.org/10.5301/jbm.5000248
  17. DUARTE, J. W. ; MISZPUTEN, Sender Jankiel ; PASTRELO, M. M. ; AMBROGINI JR., ORLANDO ; VISNIAUSKAS, B. ; CHAGAS, J. R. ; PIMENTAA, C. A. M. ; FORONES, N. M. ; PAIOTTI, A. P. R.. TPMT gene polymorphisms and drug interactions: the influence on the axathioprine therapeutic response in IBD. JOURNAL OF PHARMACEUTICAL BIOLOGY. v. JOURNAL OF PHARMACEUTICAL BIOLOGY, p. 103-110, 2016.
  18. PAZINE, VANESSA LIMA ; Silva RM ; SILVA, T. D. ; ARTIGIANI NETO, R. ; RIBEIRO, D. A. ; FORONES, N. M.. Oral Concentrated Grape Juice Suppresses Expression of NF-kappa B, TNF-α and iNOS in Experimentally Induced Colorectal Carcinogenesis in Wistar Rats. Asian Pacific Journal of Cancer Prevention. v. Asian Pacific Journal of Cancer Prevention, p. 947-952, 2015. http://dx.doi.org/10.7314/apjcp.2015.16.3.947
  19. AGUIAR, PEDRO NAZARETH ; TADOKORO, HAKARU ; FORONES, NORA MANOUKIAN ; DE MELLO, RAMON ANDRADE. Treating operable patients with gastric cancer: Macdonald's protocol versus adjuvant chemotherapy. Future Oncology. v. Future Oncology, p. 2247-2249, 2015. http://dx.doi.org/10.2217/fon.15.141
  20. AGUIAR, PEDRO NAZARETH ; Ribas C ; FORONES NM. Individualized Chemotherapy for Metastatic Gastric Cancer: Retrospective Data from a University Hospital in Brazil. Asian Pacific Journal of Cancer Prevention. v. Asian Pacific Journal of Cancer Prevention, p. 5289-5296, 2015. http://dx.doi.org/10.7314/apjcp.2015.16.13.5289
  21. Teixeira Y ; Lima, J. M. ; Souza ALAPO ; AGUIAR, PEDRO NAZARETH ; SILVA, TIAGO D ; FORONES NM. HUMAN DNA QUANTIFICATION IN THE STOOLS OF PATIENTS WITH COLORECTAL CANCER. Arquivos de Gastroenterologia (Online). v. Arquivos de Gastroenterologia (Online), p. 293-298, 2015. http://dx.doi.org/10.1590/s0004-28032015000400008
  22. SILVA, ROSEANE MENDES ; CAMPANHOLO, VANESSA MARIA DE LIMA PAZINE ; PAIOTTI, ANA PAULA RIBEIRO ; NETO, RICARDO ARTIGIANI ; Oshima, Celina Tizuko Fujiyama ; Ribeiro, Daniel Araki ; FORONES, NORA MANOUKIAN. Chemopreventive activity of grape juice concentrate (G8000TM) on rat colon carcinogenesis induced by azoxymethane. Environmental Toxicology and Pharmacology. v. Environmental Toxicology and Pharmacology, p. 870-875, 2015. http://dx.doi.org/10.1016/j.etap.2015.09.012
  23. AGUIAR, PEDRO NAZARETH ; TADOKORO, HAKARU ; FORONES, NORA MANOUKIAN ; DE MELLO, RAMON ANDRADE. MMR deficiency may lead to a high immunogenicity and then an improvement in anti-PD-1 efficacy for metastatic colorectal cancer. Immunotherapy (Print). v. Immunotherapy (Print), p. imt.15.84, 2015. http://dx.doi.org/10.2217/imt.15.84
  24. HOFF, P. M. ; SARAGIOTTO, D. F. ; BARRIOS, C. H. ; DEL GIGLIO, A. ; COUTINHO, A. K. ; ANDRADE, A. C. ; DUTRA, C. ; FORONES, N. M. ; CORREA, M. ; PORTELLA, M. D. S. O. ; PASSOS, V. Q. ; CHINEN, R. N. ; VAN EYLL, B.. Randomized Phase III Trial Exploring the Use of Long-Acting Release Octreotide in the Prevention of Chemotherapy-Induced Diarrhea in Patients With Colorectal Cancer: The LARCID Trial. Journal of Clinical Oncology. v. Journal of Clinical Oncology, p. 1006-1011, 2014. http://dx.doi.org/10.1200/JCO.2013.50.8077
  25. CAMPANHOLO, VANESSA MARIA DE LIMA PAZINE ; FELIPE, ALEDSON VITOR ; LIMA, JACQUELINE MIRANDA DE ; PIMENTA, CÉLIA APARECIDA MARQUES ; VENTURA, ROGÉRIA MARIA ; FORONES, NORA MANOUKIAN. -765 G>C POLYMORPHISM OF THE COX-2 GENE AND GASTRIC CANCER RISK IN BRAZILIAN POPULATION. Arquivos de Gastroenterologia (Impresso). v. Arquivos de Gastroenterologia (Impresso), p. 79-83, 2014. http://dx.doi.org/10.1590/S0004-28032014000200002
  26. FELIPE, ALEDSON V ; OLIVEIRA, J. ; CHANG, P. ; MORAES, A. A. F. S. ; Silva TD ; TUCCI-VIEGAS, V. M. ; FORONES NM. Establishment and Partial Characterization of an Epirubicin-Resistant Gastric Cancer Cell Line with Upregulated ABCB1. Asian Pacific Journal of Cancer Prevention. v. Asian Pacific Journal of Cancer Prevention, p. 6849-6853, 2014. http://dx.doi.org/10.7314/apjcp.2014.15.16.6849
  27. Barao K ; Vicente MA ; Silva TD ; OYAMA, L. M. ; Felipe AV ; Forones NM. Grape Juice Concentrate (G8000tm) Modulates Apoptosis but not Oxidative Stress following Rat Colon Carcinogenesis induced by Azoxymethane. Toxicology Mechanisms and Methods. v. Toxicology Mechanisms and Methods, p. 1-25, 2014. http://dx.doi.org/10.3109/15376516.2014.989556
  28. GOMES, T. S. ; CTF Oshima ; Forones NM ; LIMA, F. O. ; Ribeiro DA. Expression of galectin 3 in gastric cancer. Indian Journal of Medical Research. v. Indian Journal of Medical Research, p. 26-33, 2014.
  29. FORONES, N. M.; OLIVEIRA, J. ; FELIPE, A. V. ; ARTIGIANI NETO, R. ; OSHIMA, C. T. F. ; SILVA, M. S.. Association between ABCB1 Immunohistochemical Expression and Overall Survival in Gastric Cancer Patients. Asian Pacific Journal of Cancer Prevention. v. Asian Pacific Journal of Cancer Prevention, p. 6935-6938, 2014. http://dx.doi.org/10.7314/APJCP.2014.15.16.6935
  30. Vicente MA ; Silva TD ; Barao K ; Felipe AV ; OYAMA, L. M. ; Manoukian N. The influence of nutritional status and disease on adiponectin and TNF-α; levels in colorectal cancer patients. Nutrición Hospitalaria. v. Nutrición Hospitalaria, p. 140-6, 2014. http://dx.doi.org/10.3305/nh.2014.30.1.7132
  31. FELIPE, ALEDSON VITOR ; OLIVEIRA, JULIANA DE ; CHANG, PAULA YUN JOO ; MORAES, ANDREA APARECIDA DE FATIMA SOUZA ; SILVA, TIAGO DONIZETTI DA ; TUCCI-VIEGAS, VANINA MONIQUE ; FORONES, NORA MANOUKIAN. RNA Interference: a Promising Therapy for Gastric Cancer. Asian Pacific Journal of Cancer Prevention. v. Asian Pacific Journal of Cancer Prevention, p. 5509-5515, 2014. http://dx.doi.org/10.7314/APJCP.2014.15.14.5509
  32. FIGUEIREDO JUNIOR, ADIEL GOES DE ; FORONES, NORA MANOUKIAN. STUDY ON ADHERENCE TO CAPECITABINE AMONG PATIENTS WITH COLORECTAL CANCER AND METASTATIC BREAST CANCER. Arquivos de Gastroenterologia (Impresso). v. Arquivos de Gastroenterologia (Impresso), p. 186-191, 2014. http://dx.doi.org/10.1590/S0004-28032014000300004
  33. ARTIGGIANI NETO, R. ; FORONES, N. M. ; Ribeiro DA ; GOMES, Thiago Simão ; CTF Oshima. Immunoexpression of DIABLO, AIF and cytochrome C in gastric adenocarcinoma assessed by tissue Microarray. Anticancer Research. v. Anticancer Research, p. 647-53, 2013.
  34. Vicente MA ; Barao K ; Silva TD ; FORONES, N. M.. WHAT ARE THE MOST EFFECTIVE METHODS FOR ASSESSMENT OF NUTRITIONAL STATUS IN OUTPATIENTS WITH GASTRIC AND COLORECTAL CANCER?. Nutrición Hospitalaria. v. Nutrición Hospitalaria, p. 585-91, 2013. http://dx.doi.org/10.3305/nh.2013.28.3.6413
  35. GOMES, Thiago Simão ; Noguti, Juliana ; FORONES, N. M. ; LIMA, FLAVIO OLIVEIRA ; DOBO, Cristine ; FERNANDES JUNIOR, JOÃO ANTÃO ; Oshima, Celina Tizuko Fujiyama ; OSHIMA, C. T. F. ; Ribeiro, Daniel Araki. Correlation analysis of c-myc, p21WAF/CIP1, p53, C-erbB-2 and COX-2 proteins in esophageal squamous cell carcinoma. Pathology, Research and Practice (Print). v. Pathology, Research and Practice (Print), p. 6-9, 2013. http://dx.doi.org/10.1016/j.prp.2012.08.011
  36. FORONES, NORA. DNA methylation as an epigenetic biomarker in colorectal cancer. Oncology Letters. v. Oncology Letters, p. 1687-1692, 2013. http://dx.doi.org/10.3892/ol.2013.1606
  37. FORONES, NORA. Study of the polymorphisms of cyclooxygenase-2 (-765G>C) and 5-lipoxygenase (1708G>A) in patients with colorectal cancer. Oncology Letters. v. Oncology Letters, p. 512-518, 2013. http://dx.doi.org/10.3892/ol.2013.1732
  38. FORONES, N. Body mass index: different nutritional status according to WHO, OPAS and Lipschitz classifications in gastrointestinal cancer patients. Arquivos de Gastroenterologia (Impresso). v. Arquivos de Gastroenterologia (Impresso), p. 169-171, 2012. http://dx.doi.org/10.1590/S0004-28032012000200013
  39. SILVA, T.D. ; FELIPE, A.V. ; PIMENTA, C.A.M. ; BARÃO, K. ; FORONES, N. M.. CYP2E1 RsaI and 96-bp insertion genetic polymorphisms associated with risk for colorectal cancer. Genetics and Molecular Research. v. Genetics and Molecular Research, p. 3138-3145, 2012. http://dx.doi.org/10.4238/2012.September.3.2
  40. Oliveira J ; Felipe AV ; Pimenta CAM ; Chang P ; Massud J ; FORONES, N. M.. Association between the C3435T single-nucleotide polymorphism of multidrug resistance 1 gene and risk of gastric cancer. Molecular Medicine Reports. v. Molecular Medicine Reports, p. 395-398, 2012. http://dx.doi.org/10.3892/mmr.2012.926
  41. FELIPE, ALEDSON V ; SILVA, TIAGO D ; PIMENTA, CÉLIA A ; KASSAB, PAULO ; Forones, Nora M. lnterleukin-8 gene polymorphism and susceptibility to gastric cancer in a brazilian population. Biological Research (Print). v. Biological Research (Print), p. 369-374, 2012. http://dx.doi.org/10.4067/S0716-97602012000400007
  42. FORONES, N. M.; POVEGLANO, L. Z. ; CTF Oshima ; LIMA, F. O.. Immunoexpression of Galectin-3 in Colorectal Cancer and its Relationship with Survival. Journal of Gastrointestinal Cancer (Print). v. Journal of Gastrointestinal Cancer (Print), p. 217-221, 2011. http://dx.doi.org/10.1007/s12029-010-9189-1
  43. FORONES, N. M.; Santos NRA ; Gomes TS ; CTF Oshima ; ARGENTINI, R. ; ARTIGGIANI NETO, R.. Imunoexpression of Ki-67 and p53 in Rectal Cancer Tissue After Treatment with Neoadjuvant Chemoradiation. Journal of Gastrointestinal Cancer (Print). v. Journal of Gastrointestinal Cancer (Print), p. 34-39, 2011. http://dx.doi.org/10.1007/s12029-010-9225-1
  44. Silva TD ; Felipe AV ; LIMA, J. M. ; CTF Oshima ; FORONES, N. M.. N-Acetyltransferase 2 genetic polymorphisms and risk of colorectal cancer. World Journal of Gastroenterology. v. World Journal of Gastroenterology, p. 760-765, 2011. http://dx.doi.org/10.3748/wjg.v17.i6.760
  45. FORONES, N. M.; Gomes TS ; CTF Oshima ; SEGRETO, H. ; COSTA, H. ; LIMA, F. O. ; Ribeiro DA. The extrinsic apoptotic signaling pathway in gastric adenocarcinomas assessed by tissue microarray. Pathology, Research and Practice (Print). v. Pathology, Research and Practice (Print), p. 613-617, 2011. http://dx.doi.org/10.1016/j.prp.2011.06.010
  46. Bang YJ ; Van Cutsem E ; Feyereislova A ; Chung HC ; Shen L ; Sawaki A ; Lordick F ; Ohtsu A ; Omuru Y ; Sato H ; Aprile G ; Kulikov E ; Hill J ; Lehle M ; J, R. ; Kang YK ; Toga Trial Investigators ; FORONES, N. M.. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial.. The Lancet (North American edition). v. The Lancet (North American edition), p. 687-697, 2010.
  47. MEDEIROS, MARTA ; Oshima, Celina Tizuko Fujiyama ; FORONES, NORA MANOUKIAN. Depression and Anxiety in Colorectal Cancer Patients. Journal of Gastrointestinal Cancer (Print). v. Journal of Gastrointestinal Cancer (Print), p. 179-184, 2010. http://dx.doi.org/10.1007/s12029-010-9132-5

© 2013 - 2023 Universidade Federal de São Paulo - Unifesp

Rua Botucatu, 740, 5º andar, sala 562, Edifício Octávio de Carvalho - Vila Clementino • CEP 04023-062 - São Paulo - SP 

+55 11 3385-4100 Ramal 3027 / +55 11 5576-4228 • ppg.medicinatranslacional@unifesp.br